Oh, I liked this very much! Wilson's isolation was so apparent, so well-done throughout the whole thing, and it was heartbreaking. I also loved House's diagnosis of what had been going on, especially the way he does it with guns blazing.

You shifted tenses (from past to present) in the last paragraph, but I loved the very last line, the way Wilson is still disassociating himself--when it's House doing the comforting (and how fabulous, that House does what Wilson really needs!), you know you're in trouble.

You mentioned in comments this is your first House fic? I will look forward to more from you!